Trial Master File + Clinical Document Management Services
Providing clinical compliance consulting and TMF management services through all phases of drug development.
Headquartered in the San Francisco Bay Area, Sentinel has the technological and logistical capacity to represent US based pharmaceutical clients as well as international firms. Our team specializes in turning clinical trial challenges into operational excellence.Through our experience and knowledge, we offer high-quality services and always deliver on our promise to ensure efficiency, accuracy and compliance. We bring extensive experience and professionalism to every project and customize our support to your individual needs and concerns.Client Services
Inspection Readiness
Our team has deep experience preparing and conducting internal audits and regulatory inspections. We can help you identify and mitigate areas of risk to proactively address gaps that could result in findings. Our goal is to create a complete, inspection-ready Trial Master File which can stand up to regulatory scrutiny.
TMF Management
Sentinel consultants perform preliminary TMF stakeholder interviews and root cause analyses to create customized solutions. Our diagnostic process facilitates the implementation of flexible, powerful TMF solutions geared toward your organization’s needs. 
Systems Implementation and Innovation
Are you setting up a new eTMF System or updating an existing system? Sentinel has experience using many major eTMF systems and can help you evaluate which eTMF system will make your TMF inspection-ready. Our team of consultants can also help you create real-time dashboards, advanced reporting, and integrate your TMF with EDC, IRT, CTMS and other e-clinical systems. “Good management consists in showing average people how to do the work of superior people.”
– John Rockefeller
Get in Touch
Please reach out to with any questions. You can contact us through email or through the contact us button below. We are a team of experts and happy to talk you through your current situation and needs.